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1- LEUKEMIA

Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione

Biosci Biotechnol Biochem. 2009 Feb;73(2):280-7. Epub 2009 Feb 7. Tsai CF, Hsu YW, Chen WK, Ho YC, Lu FJ.,Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.

Electrolzyed-reduced water (ERW) is a higher pH and lower oxidation-reduction potential water. In the present study, we examined the enhanced effect of ERW in the apoptosis of leukemia cells (HL-60) induced by glutathione (GSH). An enhanced inhibitory effect on the viability of the HL-60 cells was observed after treatment with a combination of ERW with various concentrations of GSH, whereas no cytotoxic effect in normal peripheral blood mononuclear cells was observed. The results of apoptotic related protein indicated that the induction of HL-60 cell death was caused by the induction of apoptosis through upregulation of Bax and downregulation of Bcl-2. The results of further investigation showed a diminution of intracellular GSH levels in ERW, and combination with GSH groups. These results suggest that ERW is an antioxidant, and that ERW, in combination with GSH, has an enhanced apoptosis-inducing effect on HL-60 cells, which might be mediated through the mitochondria.

2- Use of Ionized water in heart disease and toxins.

Prof. Kuwata Keijiroo, Doctor of Medicine

"In my opinion, the wonder of antioxidant water is the ability to neutralize toxins; but it is not a medicine. The difference is that medicine can only apply to individual cases, whereas the antioxidant water can be consumed generally and its neutralizing power is something which is very much unexpected. Now, in brief, let me introduce to you a heart disease case and how it was cured.

The patient was a 35 years old male suffering from vascular heart disease. For 5 years, his sickness deteriorated. He was in the Setagays Government Hospital for treatment.

Last year, in August, his relatives were in despair and expected he would not live much longer. It so happened at that time that the victim's relative came across antioxidant water processor. His illness responded well and he is now on the road to recovery."

(In the United States, cardiovascular diseases account for more than one-half of the approximate 2 million deaths occurring each year…. It is estimated that optimal conditioning of drinking water could reduce this cardiovascular disease mortality rate by as much as 15 percent in the United States) From: Report of the Safe Drinking Water Committee of the National Academy of Sciences, 1977

3-Use of Ionized water in skin disease.

Eczema

Prof. Tamura Tatsuji, Keifuku Rehabilitation Center

"Eczema is used to describe several varieties of skin conditions, which have a number of common features. The exact causes of eczema are not fully understood. I many cases, eczema can be attributed to external irritants. Let me introduce a patient who recovered from skin disease after consuming the antioxidant water. This patient suffered 10 years of eczema and could not be cured effectively even under specialist treatment. This patient, who is 70 years of age, is the president of a vehicle parts company. After the war, his lower limbs suffered acute eczema, which later became chronic. He was repeatedly treated in a specialist skin hospital.

The left limb responded well to treatment, but not so on the right limb. He suffered severe itchiness, which, when scratched led to bleeding. During the last 10 years, he was seen and treated by many doctors. When I first examined him, his lower limb around the joints was covered with vesicles. Weeping occurred owing to serum exuding from the vesicles.

I advised him to try consuming antioxidant water. He bought a unit and consumed the antioxidant water religiously and used the acidic water to bathe the affected areas. After 2 weeks of treatment the vesicles dried up. The eczema was completely cleared without any relapse after 1½ month."

4- Use of Ionized water in allergies

Prof. Kuninaka Hironaga, Head of Kuninaka Hospital

"Mr. Yamada, the head of Police Research Institute, suffered from severe allergy. He was treated repeatedly by skin specialist, but with no success. Then he started consuming antioxidant water. The allergy responded very well and was soon completely cured. No relapse had occurred, although he had taken all kinds of food. He was most grateful and excited about this treatment.

As for myself, I had also suffered severe allergy. Ever since I began to consume antioxidant water, the allergy has recovered. Since then, I started a research on the effectiveness of antioxidant water.

I discovered that most allergies are due to acidification of body condition and is also related to consuming too much meat and sugar. In every allergy case, the patient's antioxidant minerals are excessively low which in turn lower the body resistance significantly. The body becomes overly sensitive and develops allergy easily. To stabilize the sensitivity, calcium solution in injected into the vein. Therefore, it is clear that the antioxidant water has ionic calcium, which can help alleviate allergy.

The ionic calcium not only enhances the heart, urination, and neutralization of toxins but controls acidity. It also enhances the digestive system and liver function. This will promote natural healing power and hence increase its resistance to allergy. In some special cases of illness, which do not respond to drugs, it is found, it is found to respond well to antioxidant water."

5- USE OF IONIZED WATER IN DIABETES TREATMENT

Jin Man Kim Division of Life Science, R&D center, Sunkyong Industries, Kazuhito Yokoyama Department of Public Health, Faculty of Medicine, The University of Tokyo

This study was carried out to evaluate the effects of alkaline ionized water (AIW) on spontaneously diabetic GK-rats fed sucrose for aggravation of diabetes mellitus.

One half of the 32 GK rats was given AIW and the other was given tap water (TW). These two groups were further divided into two subgroups by fed with or without 30% sucrose solution (8 in each group). In blood glucose level, sucrose fed TW group was significantly higher than the other groups. Sucrose fed both AIW and TW groups were significantly increased in body weight as compared to TW group. In serum malondialdehyde (MDA), a marker of lipid peroxide, sucrose fed TW group was significantly higher than AIW and TW groups.

It is suggested that AIW (Alkaline Ionized Water) supplementation may inhibit the increase of blood glucose and lipid peroxide levels in diabetes mellitus.

6- Use of Ionized water in treating Acidosis

Prof. Kogure Keizou, Kogure Clinic of Juntendo Hospital

"The stomach is readily upset both by diseases affecting the stomach and by other general illnesses. In addition, any nervous tension or anxiety frequently causes gastric upset.

The important role of antioxidant water in our stomach is to neutralize the secretion and strengthen its functions. Usually, after consuming the antioxidant water for 1 to 3 minutes, the gastric juice increase to 1½ times. For those suffering from achlorhydria ( low in gastric juice ) the presence of antioxidant water will stimulate the stomach cells to secrete more gastric juice. This in turn enhances digestion and absorption of minerals. However, those with hyperchlorhydria ( high in gastric juice ), the antioxidant water neutralizes the excessive gastric juice. Hence, it does not create any adverse reaction. According to the medical lecturer from Maeba University, the pH of the gastric secretion will still remain normal when antioxidant water is consumed. This proves the ability of the antioxidant water to neutralize as well as to stimulate the secretion."

7-Alkaline Water and Stomach Acid

by Sang Whang
Among the people who question the validity of alkaline water, the biggest question is, "What happens to the alkaline water once it reaches the stomach, which is highly acidic?" People who have some knowledge of the human body, including medical doctors, ask this question.

Let me answer that question once and for all to erase any doubts about the health benefits of alkaline water.

In order to digest food and kill the kinds of bacteria and viruses that come with the food, the inside of our stomach is acidic. The stomach pH level is maintained at around 4. When we eat food and drink water, especially alkaline water, the pH level inside the stomach goes up. When this happens, there is a feedback mechanism in our stomach to detect this that commands the stomach wall to secrete more hydrochloric acid into the stomach to bring the pH level back to 4. So the stomach becomes acidic again. When we drink more alkaline water, more hydrochloric acid is secreted to maintain the stomach pH value. It seems like a losing battle.

However, when you understand how the stomach wall makes hydrochloric acid, your concerns will disappear. As pathologists explain, there is no hydrochloric acid pouch in our body. If there were, it would burn a hole in our body. The cells in our stomach wall must produce it on an instantly-as-needed basis. The ingredients in the stomach cell that make hydrochloric acid (HCl) are carbon dioxide (CO2), water (H2O), and sodium chloride (NaCl) or potassium chloride (KCl).NaCl + H2O + CO2 = HCl + NaHCO3, or KCl + H2O + CO2 = HCl + KHCO3 .

As we can see, the by-product of making hydrochloric acid is sodium bicarbonate (NaHCO3) or potassium bicarbonate (KHCO3), which goes into blood stream. These bicarbonates are the alkaline buffers that neutralize excess acids in the blood; they dissolve solid acid wastes into liquid form. As they neutralize the solid acidic wastes, extra carbon dioxide is released, which is discharged through the lungs. As our body gets old, these alkaline buffers get low; this phenomenon is called acidosis. This is a natural occurrence as our body accumulates more acidic waste products. There is, therefore, a relationship between the aging process and the accumulation of acids.

By looking at the pH value of the stomach alone, it seems that alkaline water never reaches the body. But when you look at the whole body, there is a net gain of alkalinity as we drink alkaline water. Our body cells are slightly alkaline. In order for them to produce acid, they must also produce alkaline, and vice versa; just as a water ionizer cannot produce alkaline water without producing acid water, since tap water is almost neutral.

When the stomach pH value gets higher than 4, the stomach knows what to do to lower it. However, if the pH value goes below 4, for any reason, the stomach doesn't know what to do. That's why we take Alka-Seltzer, which is alkaline, to relieve acidic stomach gas pain. In this case, hydrochloric acid is not produced by the stomach wall, therefore, no alkaline buffer is being added to the blood stream.

Let me give you another example of a body organ that produces acid in order to produce alkaline. After the food in the stomach is digested, it must come out to the small intestine. The food at this point is so acidic that it will damage the intestine wall. In order to avoid this problem, the pancreas makes alkaline juice (known as pancreatic juice). This juice is sodium bicarbonate, and is mixed with the acidic food coming out of the stomach. From the above formulae, in order to produce bicarbonates, the pancreas must make hydrochloric acid, which goes into our blood stream.

We experience sleepiness after a big meal (not during the meal or while the food is being digested in the stomach), when the digested food is coming out of the stomach; that’s the time when hydrochloric acid goes into our blood. Hydrochloric acid is the main ingredient in antihistamines and that is what causes drowsiness.

Alkaline or acid produced by the body must have an equal and opposite acid or alkaline produced by the body; therefore, there is no net gain. However, alkaline supplied from outside the body, like drinking alkaline water, results in a net gain of alkalinity in our body.

8.high blood pressure

Pro. Kuninaka Hironage, Head of Kuninaka Hospital

"For over 10 years of my experience, my concept toward minerals, especially pertaining to ionic calcium in high blood pressure and other diseases is most significant.

In accordance to the theory of medical Professor Gato of Kyushu University on Vitamin K (because vitamin K enables the blood calcium to increase), or the consumption of more ionized water , the effectiveness of the increase in the calcium in high blood pressure is most significant. Too many fats in the diets, which lead to the deposition of cholesterol on the blood vessels, which in turn constrict the blood flow, cause most illnesses such as high blood pressure.

By drinking ionized water for a period of 2 to 3 months, the blood pressure should slowly drop, because the ionized water is a good solvent, which dissolves the cholesterol in the blood vessels."

9. Gyneocological conditions

Prof. Watanabe Ifao. Watanabe Hospital, Japan

"Ionized water improves body constituents and ensures effective healing to many illnesses. The uses of ionized water in gynecological patients habe proved to be very effective. The main reason for its effectiveness is that this water can neutralize toxins.
When given ionized to pre-eclamptic toxemia cases, the results re very significant. During my long years of servicing the pre-eclamptic toxemia cases, I found that the women with pre-eclamptic toxemia who consumed ionized water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group has intelligence above average."

10. Heart Disease

Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

"In my opinion, the wonder of ionized water is the ability neutralizes toxins, but it is not a medicine. The difference is that the medicine can only apply to each and individual case. whereas the ionized water can be consumed generally and its neutralizing power is something which is very much unexpected. Now, in brief, let me introduce to you a heart disease case and how it was cured.

The patient was a 35 years old male suffering from vascular heart disease. For 5 years, his sickness deteriorated. He was in the Setagays Government Hospital for treatment.

During those 5 years, he had been in and out of the hospital 5 to 6 times. He had undergone high tech examinations such as angiogram by injecting VINYL via the vein into the heart. He consulted and sought treatment from many good doctors where later he underwent a major surgical operation. upon his discharge from the hospital, he quit his job to convalesce. However, each time when his illness relapsed, the attack seemed to be even more severe. Last year, in August, his relatives were in despair and expected he would not live much longer. It so happened at that time that the victim's relative came across ionized water processor. His illness responded well and he is now on the road to recovery."

Note: In the United States, cardiovascular diseases account for more than one-half of the approximate 2 million deaths occurring each year. It is estimated that optimal conditioning of drinking water could reduce this cardiovascular disease mortality rate by as much as 15 percent in the United States"

From: Report of the Safe Drinking Water committee of the National Academy of Sciences, 1977

11. Eczema

Prof. Tamura Tatsuji, Keifuku Rehabilitation Center, Japan

"Eczema is used to describe several varieties of skin conditions, which have a number of common features. The exact cause or cause of eczema are not fully understood. I many cases, eczema can be attributed by external irritants.

Let me introduce a patient who recovered from skin disease after consuming the ionized water. This patient suffered 10 years of eczema and could not be cured effectively even under specialist treatment. This patient, who is 70 years.. " age, is the President of a vehicle spare parts company. After the war, his lower limbs suffer acute eczema, which later became chronic. He was repeatedly treated in a specialist skin hospital.

I advised him to try consuming ionized water. He bought a unit and consumed the ionized water religiously and used the acidic water to bathe the affected areas. After 2 weeks of treatment the vesicles dried up. The eczema was completely cleared without any relapse after 1 1/2 month."

12.Allergy

Prof. Kuninaka Hironaga, Head of Kuninaka-Hospital, Japan

"Mr. Yamada, the head of Police Research Institute, suffered from severe allergy. He was treated repeatedly by skin specialist, but with no success. Then he started consuming ionized water. The allergy responded very well and was soon completely cured. No relapse had occurred, although he had taken all kinds of food. He was most grateful and excited about this treatment.

As for myself, I had also suffered severe allergy. Ever since I began to consume ionized water, the allergy has recovered. Since then, I started a research on the effectiveness of ionized water.

I discovered that most allergies is due to acidification of body condition and is also related to consuming too much meat and sugar. In every allergy case, the patient's antioxidant minerals are excessively low which in turn lower the body resistance significantly. The body becomes overly sensitive and develops allergy easily. To stabilize the sensitivity. calcium solution in injected into the vein. Therefore, it is clear that the ionized water has ionic calcium, which can help alleviate allergy.

13.Digestive System Problem

Prof. Kogure Keizou, Kogure Clinic of Juntendo Hospital, Japan

"The stomach is readily upset both by diseases affecting the stomach and by other general illnesses. In addition, any nervous tension or anxiety frequently causes gastric upset, vague symptoms when they are under some strain.

The important role of ionized water in our stomach is to neutralize the secretion and strengthen it s functions. Usually, after consuming the ionized water for 1 to 3 minutes, the gastric juice increase to 1 1/2 times. For those suffering from hyperchlorhydria or achlorhydria (low in gastric juice ) the presence of ionized water will stimulate the stomach cells to secrete more gastric juice. This in turn enhances digestion and absorption of minerals.

However, on the other hand, those with hyperchlorhydria(high in gastric juice), the ionized water neutralizes the excessive gastric juice. Hence, it does not create any adverse reaction.

According to the medical lecturer form Maeba University, the pH of the gastric secretion will still remain normal when ionized water is consumed. This proves that the ability of the ionized water is able to neutralize as well as to stimulate the secretion."

14.Diabetes

Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

"When I was serving in the Fire Insurance Association, I used to examine many diabetic patients. Besides treating them with drugs, I provided them with ionized water. After drinking ionized water for one month, 15 diabetic patients were selected and sent to Tokyo University for further test and observations.

Initially, the more serious patients were a bit apprehensive about the treatment. When the ionized water was consumed for some time, the sugar in the blood and urine ranged from a ratio of 300 mg/l to 2 mg/ dc. There was a time where the patient had undergone 5 to 6 blood tests a day and detected to be within normal range. Results also showed that even 1 1/2 hour after meals, the blood sugar and urine ratio was 100 mg/dc 0 mg/dc. The sugar in the urine has completely disappeared."

More Americans than ever before are suffering from diabetes, with the number of new cases averaging almost 800,000 each year. The disease has steadily increased in the United States since 1980, and in 1998, 16 million Americans were diagnosed with diabetes (10. million diagnosed, 5.4 million undiagnosed) Diabetes is the seventh leading cause of death in the United States, and more than 193,000 died from the disease and its related complication in 1996. The greatest increase-76 percent-occurred in people age 30 to 30.

From: U. S. Department of Health and Human Services, October 13, 2000 Fact Sheet.

15.Obesity

Prof. Hatori Tasutaroo, Head of Akajiuiji Blood Centre, Yokohama Hospital, Faitama District

"Due to a higher standard of living, our eating habits have changed. We consume too much proteins, fats and sugar. The excess fats and bafbohydrates are in the body as fats. In the present lifestyles, Americans are more extravagant an food compared to the Japanese. Due to this excessive intake obesity is a significant problem. Normally, one out of five males and one out of four females is obese.

The degree of "burn-out" in food intake largely depends on the amount on intake of vitamins and minerals. When excessive intake of proteins, carbohydrates and fats occurs, the requirement for vitamins and minerals increases. However, there is not much research carried out pertaining to the importance of vitamins and minerals.

Nowadays, many people suffer from acidification that leads to diabetes, heart diseases, cancer, live and kidney diseases. If our food intake can be completely burned off, then there is no deposition of fats. Obviously, there will be no acidification problem and hence there should not be any sign of obesity.

The ionized water contains an abundance of ionic calcium. This ionic calcium helps in the "burn-off" process. By drinking ionized water, it provides sufficient minerals for our body. As a result, we do not need to watch our diet to stay slim.

Hence, ionized water is a savior for those differing from obesity and many adult diseases, providing good assistance in enhancing hood health."

16.Hypochlorhydria or achlorhydria

Prof. Kuninaka Hironage, Head of Kuninaka Hospital

"Too many fats in the diets, which lead to the deposition of cholesterol on the blood vessels, which in turn constrict the blood flow, cause most illnesses such as high blood pressure. In accordance with the theory of Professor Gato of Kyushu University on Vitamin K (because vitamin K enables the blood calcium to increase ), or the consumption of more antioxidant water, the effectiveness of the increase in the calcium in high blood pressure is most significant. The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels."

17.Kidney Disease

Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

Dr Kerijiroo explains that for severe kidney failure, water intake has to be restricted. However whereas ordinary tap water "contains phosphate, calcium carbonate and the acidic ions. . . . [that] tend to reduce the efficiency of the calcium ions. . . ." he feels that in controlled amounts, Alkaline Ionic water will "strengthen the heart and increase urination."

He goes on to claim that over the next six to twelve months, the patient should maintain an alkaline diet (reduced animal protein) and continue drinking the Alkaline Ionic water to reduce the amounts of urea and uric acid in the blood. He also feels that, through his clinical experience that patients undergoing kidney dialysis should also drink Alkaline Ionic water as well as those patients with kidney disease who do not respond to drugs.

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